Table 2.
Frequency of genotypes and alleles among study subjects based upon the significance of coronary artery stenosis stratification in CAD patients.
| SNPs | Genotype | N (%) | Group A Insignificant stenosis |
Group B Significant stenosis |
χ 2 | P |
|---|---|---|---|---|---|---|
| rs599839 A>G | AA | 107 (48.4) | 48 (56.5) | 59 (43.4) | 3.668 | 0.159 |
| AG | 36 (16.3) | 11 (12.9) | 25 (18.4) | |||
| GG | 78 (35.3) | 26 (30.6) | 52 (38.2) | |||
|
| ||||||
| MAF | G (0.434) | G (0.371) | G (0.474) | 3.682 | 0.032 | |
|
| ||||||
| rs646776 T>C | TT | 170 (76.9) | 73 (80.2) | 97 (72.9) | 1.568 | 0.456 |
| TC | 18 (8.0) | 6 (6.6) | 12 (9.0) | |||
| CC | 36 (16.1) | 12 (13.2) | 24 (18.1) | |||
|
| ||||||
| MAF | C (0.201) | C (0.165) | C (0.236) | 2.119 | 0.146 | |
|
| ||||||
| rs4970834 C>T | CC | 122 (54.2) | 48 (53.9) | 74 (54.4) | 4.147 | 0.125 |
| CT | 40 (17.8) | 11 (12.4) | 29 (21.3) | |||
| TT | 63 (28) | 30 (33.7) | 33 (24.3) | |||
|
| ||||||
| MAF | T (0.369) | T (0.425) | T (0.316) | 0.934 | 0.317 | |
Data are presented by frequency for minor allele [MAF] and P value is significant at >0.05. Frequency of alleles is presented as a percentage. Data were analyzed by chi-square test (2 degrees of freedom) with Bonferroni adjustments. Two-tailed P value is significant at <0.05.