Table 2.

Cumulative Treatment Failure at 48 Hours, Day 5, and Day 14

Treatment Group	48 h, PP, Proportion (%)	48 h, ITT, Proportion (%)	Day 5, ITT, Proportion (%)	Day 14, ITT, Proportion (%)
Amoxicillin	20/260 (7.7)	20/263 (7.6)	30/263 (11.4)	33/244 (13.5)
Penicillin	21/261 (8.0)	21/263 (8.0)	29/263 (11.0)	42/250 (16.8)
Risk difference, % (95% CI)	−0.3 (−5.0 to 4.3)	−0.4 (−5.0 to 4.2)	0.4 (−5.0 to 5.8)	−3.3 (−10.0 to 3.0)

Abbreviations: CI, confidence interval; ITT, intention to treat; PP, per protocol.