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. 2015 Mar;52(3):342–348. doi: 10.1165/rcmb.2014-0114OC

Table 1.

CD43 Polymorphism Frequencies in Control and Tuberculosis Groups

SNP,* Group Subjects with Genotype (n [%])
Genotypic Comparison
HWE P Value
00 01 11 χ2 P Value
rs11859842 T/C            
 Control 364 (0.953) 18 (0.047) 0 (0)     0.637
 All TB 347 (0.934) 21 (0.061) 2 (0.006) 2.883 0.237  
rs11150564 G/A            
 Control 218 (0.578) 137 (0.363) 22 (0.058)     0.938
 All TB 196 (0.578) 116 (0.342) 27 (0.080) 1.410 0.494  
rs4788172 G/A            
 Control 126 (0.335) 187 (0.497) 63 (0.168)     0.650
 All TB 122 (0.378) 123 (0.381) 78 (0.241) 10.92 0.004  
rs3764275 C/A            
 Control 163 (0.429) 176 (0.463) 41 (0.108)     0.523
 All TB 161 (0.491) 126 (0.384) 41 (0.125) 4.496 0.106  
rs11574552 T/C            
 Control 171 (0.451) 165 (0.476) 43 (0.113)     0.738
 All TB 143 (0.427) 133 (0.397) 59 (0.176) 5.753 0.056  
rs3764276 T/C            
 Control 381 (0.997) 1 (0.003) 0 (0)     0.980
 All TB 348 (0.997) 1 (0.003) 0 (0) 0.004 0.949  
rs2071420 A/G            
 Control 179 (0.469) 165 (0.432) 38 (0.099)     0.998
 All TB 154 (0.467) 132 (0.400) 44 (0.133) 2.197 0.333  
rs1050881 C/T            
 Control 161 (0.429) 172 (0.459) 42 (0.112)     0.698
 All TB 146 (0.465) 119 (0.379) 49 (0.156) 5.567 0.062  
rs17842268 T/C            
 Control 165 (0.440) 176 (0.469) 34 (0.091)     0.181
 All TB 161 (0.407) 127 (0.371) 54 (0.158) 11.02 0.004  
rs12596308 T/C            
 Control 156 (0.413) 180 (0.476) 42 (0.111)     0.354
 All TB 137 (0.408) 132 (0.393) 67 (0.199) 11.92 0.003  
rs12599318 G/A            
 Control 361 (0.953) 18 (0.047) 0 (0)     0.636
 All TB 315 (0.938) 19 (0.057) 2 (0.057) 2.581 0.275  

Definition of abbreviations: HWE, Hardy Weinberg equilibrium P value in control subjects; SNP, single-nucteotide polymorphism; TB, tuberculosis.

*

SNPs are listed by reference SNP ID in genomic order on chromosome 16. 0, common allele; 1, minor allele.

All TB includes pulmonary tuberculosis and tuberculous meningitis cases from the discovery cohort.