Fig. 4. Translational research and transformational changes to health care.

Driven by health care needs, PoC and PoP imaging technologies are increasingly being translated from the bench to the patient bedside via technology development and initial clinical application studies. However, these initial translational efforts frequently stall without advancing toward commercialization and wider dissemination for larger populations of patients unless supported and funded by industry, government, and/or private foundations. With such support, transformational changes can occur by first validating the imaging technology against the current standard of care, followed by successfully overcoming the challenges associated with the integration and adoption of the imaging technology as the new standard of care.