Table 2.
Summary of studies reported effect of dialysis modality on RRF
| Reference (year) | Study design | Subject characteristics | Favour CAPD | Details |
|---|---|---|---|---|
| Hiroshige et al. (1996) [51] | 6-month prospective | Prevalent 8 NIPD, 5 CCPD, 5 CAPD | Yes | Rate of change of RRF in −0.29 (NIPD) versus −0.34 (CCPD) versus +0.01 (CAPD) mL/min/month |
| Rodriguez et al. (1998) [56] | 3-year prospective | Prevalent 25 CAPD, 20 APD | No | |
| Hufnagel et al. (1999) [52] | 18-month prospective | Incident 6 NIPD, 12 CCPD, 18 CAPD | Yes | Rate of change of RRF in −0.26 (APD) versus −0.13 (CAPD) mL/min/month |
| Bro et al. (1999) [57] | 6-month randomized controlled trial | Prevalent 13 CAPD, 12 APD | No | |
| Moist et al. (2000) [28] | 3-year retrospective | Incident 722 CAPD, 310 APD | No | |
| De Fijter et al. (2000) [53] | 2-year randomized controlled trial | Incident 13 CCPD, 11 CAPD | No | |
| Gallar et al. (2000) [58] | 1-year prospective | Incident 11 CAPD, 9 APD | No | |
| Singhal et al. (2000) [59] | 4-year prospective | Incident 211 CAPD, 31 APD | No | |
| Holley et al. (2001) [60] | 9-year retrospective | Incident 11 CAPD, 9 APD | No | |
| Jansen et al. (2002) [39] | 1-year prospective | Incident 243 PD subjects | No | |
| Hidaka et al. (2003) [61] | 6-year prospective | Incident 27 CAPD, 7 APD | Yes | Approximate time to decrease 50% of RRF in CAPD is 15 months versus APD 4 months, P < 0.001 |
| Johnson et al. (2003) [36] | 6-year prospective | Incident 134 CAPD, 12 APD | No | |
| Rodriguez-Carmona (2004) [62] | 1-year prospective | Incident 53 CAPD, 51 APD | Yes | Hazard ratio of APD versus CAPD = −1.2 (−2.25 to −0.15, P = 0.02) |
| Rabindranath (2007) [63] | Systematic review of 3 RCT | 49 PD subjects | No | |
| Liao (2009) [27] | 10-year retrospective | Incident 188 CAPD, 82 APD | No | |
| Su et al. (2010) [64] | 9-year retrospective | Prevalent 140 CAPD, 32 APD | No | |
| Cnossen et al. (2010) [55] | 7-year retrospective | Incident 179 CAPD, 441 APD | No | |
| Balasubramanian et al. (2011) [54] | 5-year retrospective | Incident 178 CAPD, 13 APD | No | |
| Michels et al. (2011) [65] | 3-year retrospective | Incident 505 CAPD, 78 APD | Yes | Higher risk of loss of RRF in APD compared to CAPD in first year of treatment (adjusted hazard ratio 2.66, CI 1.66–4.44) |