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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Oct 12;1851(4):308–330. doi: 10.1016/j.bbalip.2014.10.002

Fig. 4. Crystal structure of the stabilized version of human ALOX5.

Fig. 4

The N-terminal β-barrel domain is shown in yellow, the flexible inter-domain linker (D113-L118) in magenta, the C-terminal catalytic domain in green and the iron liganding residues in red. The residues mutated in wild-type ALOX5 to get the stabilized version of the enzyme suitable for crystallization are indicated in blue. The image was constructed from the X-ray diffraction data using the PyMol software package.