Table 3.
HRs (95% CIs) for the main effect associations of incident type 2 diabetes across quartiles of serum NEFAs, MESA, N = 5,697
| Quartiles of NEFAs | Ptrend | ||||
|---|---|---|---|---|---|
| Quartile, n | 1 (n = 1,380) | 2 (n = 1,461) | 3 (n = 1,455) | 4 (n = 1,401) | |
| Range | 0.13–0.39 | 0.40–0.52 | 0.53–0.67 | 0.68–2.11 | |
| Cases, n | 124 | 166 | 181 | 186 | |
| Model 1, HR (95% CI) | 1.0 | 1.35 (1.07, 1.71) | 1.58 (1.24, 2.00) | 1.86 (1.45, 2.38) | <0.001 |
| Model 2, HR (95% CI) | 1.0 | 1.23 (0.97, 1.56) | 1.35 (1.06, 1.72) | 1.56 (1.21, 2.00) | 0.006 |
Model 1 adjusted for age, sex, race, education, field center, smoking, and alcohol use. Model 2 adjusted for model 1 plus waist circumference and hs-CRP.