Table 1.
Sexual function in women on aromatase inhibitors (AIs)
| Publication | N | Months on AIs | Assessment Questionnaire | Low Sexual Desire | Vaginal Dryness | Dyspareunia |
|---|---|---|---|---|---|---|
| Morales et al., 2004 [10] | 37 | 3 | Item written for study | 68% | 50% | 62% |
| Cella et al., 2006 [6] | 335 | 60 | FACT-ES | 34% | 18% | 17% |
| Jones et al., 2007 [17] | 808 | 12 | Item written for study | 58% | 50% | -- |
| Antoine et al., 2008 [13] | 14 | Unknown | Women's Health Questionnaire | 84% | 88% | -- |
| Oberguggenberger et al., 2011 [9] | 233 | Unknown | FACT-ES | 51% | 32% | 16% |
| Baumgart et al., 2011 [17] | 35 | Unknown | FACT-ES | -- | 42% | 62% |
| Kyvernitakis et al., 2013 [4] | 181 | 24 | Item written for study | 43%* | 57% | -- |
| Aiello Bowles et al., 2012 [19] | 314 | Unknown | Item written for study | 36% | 36% | -- |
| Fallowfield et al., 2012 [7] | 83 | 24 | FACT-ES | 32% | 17% | 13% |
FACT-ES: Functional Assessment of Cancer Treatment-Endocrine Symptoms (FACT-ES) questionnaire
*
Item was reported as “sexual problems” so it may reflect more than low desire