Fig 4. Histological aspects of wounds treated with dermal substitutes showing vascular density.

(A) Representative picture of HE-stained transversal section of a full-thickness skin wound with emphasis in blood vessels. (B) Quantification of blood vessels during the 9 days after the surgical procedure. NA numerical density that represent the number of blood vessels per mm². Data are expressed as the mean ± SEM of 5 animals. Not significant differences between the two templates were observed at any time point. # p = 0.05 Pelnac at the day 3 vs. Pelnac at day 6 by two-tailed unpaired t-test. Original magnification 400X.