Table 1. Clinical and laboratory features of studied PVNS patients.
| Total | Male | Female | Knee | Hip | |
|---|---|---|---|---|---|
| Number (%) | 237 | 101 (42.62) | 136 (57.38) | 175 (73.84) | 43 (18.14) |
| Mean age at diagnosis (mean±SD)(Y) | 35.52±15.31 | 34.65±15.24 | 36.17±15.40 | 35.70±16.12 | 32.07±10.12 |
| Gender ratio (females/males) | 1.35 (136/101) | - | - | 1.24 (97/78) | 1.53 (26/17) |
| Laterality [no.(%)] | |||||
| Left | 111(46.84) | 47(19.84) | 64(27.00) | 78(32.91) | 24(10.13) |
| Right | 119(50.21) | 50(21.10) | 69(29.11) | 91(38.40) | 18(7.59) |
| Bilateral | 7(2.95) | 4(1.69) | 3(1.26) | 6(2.53) | 1(0.42) |
| Median interval from symptoms onset to diagnosis (range) (M) | 18(0.2–600) | 19.5 (0.2–360) | 18(0.5–600) | 12(0.2–600) | 24(1–240) |
| Initial clinical symptom [no.(%)] | |||||
| Pain | 106(44.73) | 43(18.14) | 63(26.58) | 60(25.32) | 40(16.88) |
| Swelling | 53(22.36) | 22(9.28) | 31(13.08) | 66(27.85) | 0(0.00) |
| Swelling and pain | 70(29.54) | 33(13.92) | 37(15.61) | 44(18.57) | 0(0.00) |
| Other | 8(3.37) | 3(1.27) | 5(2.11) | 5(2.11) | 3(1.27) |
| Comorbidities [no.(%)] | |||||
| Avascular necrosis | 6(2.53) | 2(0.84) | 4(1.69) | 1(0.42) | 5(2.11) |
| Orthopedic intervention | 5(2.11) | 4(1.69) | 1(0.42) | 3(1.27) | 1(0.42) |
| Trauma history | 40(16.88) | 18(7.59) | 22(9.28) | 31(13.08) | 6(2.53) |
| Treatment strategies [no.(%)] | |||||
| Arthroscopy | 129(54.43) | 56(23.63) | 73(30.80) | 118(49.79) | 6(2.53) |
| Open surgery | 108(45.57) | 45(18.99) | 63(26.58) | 57(24.05) | 37(15.61) |
| Recurrence (events/total) [no.(%)] | 48/237 (20.25) | 26/101 (25.74) | 22/136 (16.18) | 42/175 (24.00) | 3/43 (6.98)* |
| Median recurrence time (range) (M) | 12(1–144) | 12(1–108) | 16.5(1–144) | 12(1–120) | 108(24–144) |
| Serum inflammatory marker | |||||
| WBC (mean ± SD) (×10 9/L) | 7.04±2.05 | 7.59±2.18 | 6.66±1.87 | 6.97±2.18 | 7.23±1.83 |
| ESR (median, IQR)(mm/h) | 13.5 (7.00, 30.00) | 11.00 (4.00, 28.00) | 14.00 (7.75, 30.25) | 13.00 (7.00, 33.00) | 10.00 (6.00, 20.00) |
| CRP (median, IQR)(mg/L) | 3.06 (1.20, 8.96) | 3.64 (1.72, 23.35) | 2.38 (1.00, 6.71) | 2.76 (1.00, 14.33) | 3.23 (1.48, 7.34) |
WBC = white blood cell count, ESR = erythrocyte sedimentation rate, CRP = C-reactive protein, IQR = interquartile range, SD = standard deviation, M = month, Y = year.
* p≤0.05