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. 2015 Mar 23;10(3):e0120793. doi: 10.1371/journal.pone.0120793

Table 1. Immunogenicity of inactivated influenza H7N9 whole virus vaccine in ferrets.

Group 1 Group 2 Group 3
HA (μg/dose) 0 1.5 1.5
Al(OH)3 (μg/dose) 300 0 300
No. of animals 4 4 4
HI Seroconversion
Prevaccination 0/4 0/4 0/4
Post dose 1 0/4 0/4 4/4
Post dose 2 0/4 4/4 4/4
HI GMT
Prevaccination <10 <10 <10
Post dose 1 <10 <10 48 (34–67) a
Post dose 2 <10 17 (9–33) 190 (98–396)
Nt Seroconversion
Prevaccination 0/4 0/4 0/4
Post dose 1 0/4 0/4 4/4
Post dose 2 0/4 4/4 4/4
Nt GMT
Prevaccination <40 <40 <40
Post dose 1 <40 <40 48 (34–67)
Post dose 2 <40 80 (30–213) 640 (143–2189)

aGeometric mean titers (95% confidence interval)