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. 2015 Mar 23;10(3):e0120496. doi: 10.1371/journal.pone.0120496

Fig 5. Abortive vaccinia virus replication and maturation in SCCF1 cells.

Fig 5

A) At 48 hours after infection, the replication centre (viral factory) is inconspicuous, only a few immature viruses (IV) were found around it. B) Two IVs were visible, one IV showed nucleoid inside thus can be identified as IVN. Neither mature viruses nor enveloped viruses were detected throughout all infected cells. C) there are two small immature viruses (IV) located within cell and in the edge of an abnormal granular virosome (VS) region. No MVs were visible there. D) The immature viruses (IV) migrate to peripheral of the cell, underneath cell membrane. They still fail to get membranous envelope even at this late stage of nearly being released out.