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. 2015 Mar 23;10(3):e0121319. doi: 10.1371/journal.pone.0121319

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© 2015 Chen et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Fig 3 — (A) The wound-healing assay revealed a significant decrease in migration in the β-catenin shRNA group (left), relative to the control group (right). (B) The wound-healing rate was significantly lower in S100A6-expressing cells, compared to the control, at 24 and 48 h. (C) The transwell assay demonstrated that β-catenin shRNA dramatically decreased the number of migrating and invading cells (×40). “I” represents β-catenin shRNA in the migration assay; “II” represents the control group in the migration assay; “III” represents β-catenin shRNA in the invasion assay; “IV” represents the control group in the invasion assay. (D) Representative statistical chart for the transwell assay, showing a significant decrease in migration (I) and invasion (II) in the β-catenin shRNA group, compared to the control group. *p < 0.05; **p < 0.01.