Table 5.
Association of LV Systolic Function With log-WMHV
| Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|
| Predictor | β (SE) | P Value | β (SE) | Part. R | P Value | β (SE) | Part. R | P Value |
| LVEF | −0.06 (0.05) | 0.25 | −0.04 (0.04) | −0.06 | 0.42 | — | — | — |
| GLS | 0.18 (0.05) | <0.01 | 0.11 (0.04) | 0.12 | <0.05 | 0.10 (0.05) | 0.11 | <0.05 |
Values in table are parameter estimates per standard deviation increase (β), standard errors (SE), and partial correlation coefficients (Part. R). Each predictor is evaluated in a separate model. Model 1, unadjusted; model 2, adjusted for age, sex, body mass index, SBP, DBP, hypertension, diabetes mellitus, hypercholesterolemia, smoking history, LV mass index, relative wall thickness, and LV diastolic dysfunction; model 3, adjusted for covariates from model 2 plus LVEF. DBP indicates diastolic blood pressure; GLS indicate global longitudinal strain; LV, left ventricular; LVEF, left ventricular ejection fraction; SBP, systolic blood pressure; and WMHV, white matter hyperintensity volume.