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. 2015 Mar 23;10(3):e0119912. doi: 10.1371/journal.pone.0119912

Fig 7. ERK and JNK inhibitors impair astrocyte proliferation and migration.

Fig 7

A and B. MEK inhibitor (U0126, 10 μM) and JNK inhibitor (sp600125, 20 μM) inhibit astrocyte proliferation by 36.3% ± 11.8% and 42.9% ± 7.8% respectively (*, p < 0.05, n = 4). C and D. MEK inhibitor (U0126, 10 μM) and JNK inhibitor (sp600125, 20 μM) inhibit astrocyte migration by 17.9% ± 3.7% and 60.0% ± 4.1% respectively (*, p < 0.05; **, p < 0.01, n = 6).