. 2015 Mar 23;10(3):e0120297. doi: 10.1371/journal.pone.0120297

Table 1. Demographic, clinical and laboratory data of patients with cryptococcal meningitis and the control groups.

Variables	CM⁺ HIV⁺	CM^- HIV⁺	CM^- HIV^-
Variables	N = 30	N = 56	N = 48
Age, years	38.1 (25–50)	38.4 (31–44)	40.1 (33–47)
Males N (%)	24 (80)	37 (66)	38 (79.1)
Years since HIV diagnosis	12.8 (9.3–18.4)	10.5 (7.1–17.8)	——
CD4⁺ T-cells count, cells/mm³	36 (19–75)	39.4 (25–54)	——
HIV load, log₁₀ copies/mL	5.1 (4.3–5.9)	5 (5–5.1)	——

Data presented are median [interquartile range, (IQR)] or percentage (No.). Groups are comparable in CD4⁺ T-cell count and HIV load in blood (p = 0.027 and 0.042, respectively).

Abreviations: CM⁺ HIV⁺, HIV-infected patients with cryptococcal meningitis; CM^- HIV⁺, HIV-infected individuals without cryptococcal meningitis; CM^- HIV^-, HIV-negative individuals without cryptococcosis.

CM^- HIV⁺ control group clinical diagnoses: syphilis (n = 7), encephalitis associated to HIV infection (n = 7), toxoplasmosis (n = 5), tension-type headache (n = 5), dementia associated to HIV (n = 5), asseptic meningitis (n = 4), progressive multifocal leucoencephalopaty (n = 3), mycobacterium disease (n = 2), viral encephalitis (n = 2), epilepsy (n = 2), cerebral primary lymphoma (n = 2), migraine (n = 2), stroke (n = 1), encephalitis by T. cruzi (n = 1), encephalitis by Paracoccidioides brasiliensis (n = 1), cerebral nocardiosis (n = 1), guillain-barré syndrome (n = 1), encephalitis by CMV (n = 1), sepsis (n = 1), glaucoma (n = 1), hypertensive encephalopaty (n = 1), unknown paresis (n = 1).

CM^- HIV^- control group clinical diagnoses: epilepsy (n = 10), migraine (n = 7), stroke (n = 6), tension-type headache (n = 6), skull trauma (n = 6), alcoholism (n = 5), dementia (n = 2), systemic erithematous lupus (n = 1), hipertensive encephalopathy (n = 1), asseptic meningitis (n = 1), viral encephalitis (n = 1).