Table 1. Patient characteristics (n = 107).
| Baseline characteristics | Mean (SD) | |
|---|---|---|
| Age (years) | 60.03 (14.78) | |
| BMI (kg/m2) | 27.45 (5.64) | |
| Weight (kg) | 81.49 (18.26) | |
| SAPS II | 22.13 (9.63) | |
| ICU (days) | 9.50 (14.05) | |
| Chronic kidney disease | 18 (15%) | |
| Creatinine at admission ICU | 1.13 (0.60) | |
| AKI | 45 (42%) | |
| AKI stage 2 and 3 | 24 (22%) | |
| RRT <48 hours after admission | 10 (9%) | |
| 28-day mortality | 10 (9%) | |
| Diagnosis/Surgery at admission | Frequency (percentage) | (IGFBP-7)*(TIMP-2) values (Median (IQR), min-max) |
| Hepatobiliary | 12 (11%) | 0.46 (0.30, 0.78), 0.22–1.78 |
| Transplant | 14 (13%) | 0.45 (0.15, 1.50), 0.04–4.18 |
| Cancer | 13 (12%) | 0.22 (0.11, 1.99), 0.02–9.50 |
| Vascular | 33 (31%) | 0.27 (0.13, 0.36), 0.02–0.87 |
| Severe Trauma | 21 (20%) | 0.38 (0.11, 1.27), 0.04–9.59 |
| Sepsis | 10 (9%) | 1.24 (0.29, 2.83), 0.08–5.91 |
| Other | 4 (4%) | |
| (IGFBP-7)*(TIMP-2) values | Median (IQR), min-max | |
| Ø AKI | 0.19 (0.10, 0.34), 0.02–1.79 | |
| AKI Stage 1 | 0.51 (0.29,2.29), 0.04–9.50 | |
| AKI Stage 2 and 3 | 1.24 (0.56, 3.00), 0.32–9.59 | |
| RRT <48 hours after admission | 1.35 (0.76, 3.39), 0.44–4.18 | |
BMI, body mass index; SAPS II, Simplified Acute Physiology Score II; ICU, intensive care unit; AKI, acute kidney injury; RRT, renal replacement therapy; SD, standard deviation; IGFBP7, insulin-like growth factor-binding protein 7; TIMP-2, tissue inhibitor of metalloproteinase.