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. 2015 Mar 23;10(3):e0118789. doi: 10.1371/journal.pone.0118789

Table 1. rs17525495 is associated with susceptibility to bacterial meningitis.

subject allele genotype freq P P P HWE j
group freq a C b CC/CT c /TT CC/CT/TT (add d ) OR (95% CI) e (gen f ) OR (95% CI) g OR (95% CI) h (rec i ) OR (95% CI) control P
control 0.67 339/326/86 0.45/0.43/0.11 0.57
BM all 0.61 155/168/67 0.40/0.43/0.17 0.01 1.26 (1.06–1.50) 0.02 1.13(0.86–1.47) 1.70 (1.18–2.47) 0.008 1.60 (1.13–2.27) 0.07
BM def k 0.61 124/133/55 0.40/0.43/0.18 0.01 1.27 (1.05–1.54) 0.02 1.12(0.84–1.49) 1.75 (1.18–2.60) 0.008 1.65 (1.15–2.39) 0.07

afrequency

bcytosine

cthymine

dadditive model

eodds ratio (95% confidence interval)

fgeneral model; a genotypic model where one genotype group (e.g. CC group) is baseline

gestimates of odds for general model, comparing baseline (CC) to CT

hestimates of odds for general model comparing baseline (CC) to TT

irecessive model

jHardy Weinberg Equilibrium

kdefinite. NB: data for dominant and heterozygote advantage model were not significant and are not shown here.