Table 1. rs17525495 is associated with susceptibility to bacterial meningitis.
subject | allele | genotype | freq | P | P | P | HWE j | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
group | freq a C b | CC/CT c /TT | CC/CT/TT | (add d ) | OR (95% CI) e | (gen f ) | OR (95% CI) g | OR (95% CI) h | (rec i ) | OR (95% CI) | control P |
control | 0.67 | 339/326/86 | 0.45/0.43/0.11 | 0.57 | |||||||
BM all | 0.61 | 155/168/67 | 0.40/0.43/0.17 | 0.01 | 1.26 (1.06–1.50) | 0.02 | 1.13(0.86–1.47) | 1.70 (1.18–2.47) | 0.008 | 1.60 (1.13–2.27) | 0.07 |
BM def k | 0.61 | 124/133/55 | 0.40/0.43/0.18 | 0.01 | 1.27 (1.05–1.54) | 0.02 | 1.12(0.84–1.49) | 1.75 (1.18–2.60) | 0.008 | 1.65 (1.15–2.39) | 0.07 |
afrequency
bcytosine
cthymine
dadditive model
eodds ratio (95% confidence interval)
fgeneral model; a genotypic model where one genotype group (e.g. CC group) is baseline
gestimates of odds for general model, comparing baseline (CC) to CT
hestimates of odds for general model comparing baseline (CC) to TT
irecessive model
jHardy Weinberg Equilibrium
kdefinite. NB: data for dominant and heterozygote advantage model were not significant and are not shown here.