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. 2015 Mar 23;10(3):e0122446. doi: 10.1371/journal.pone.0122446

Fig 4. Effect of mitochondrial metabolism (aerobic glycolysis) on ASMC proliferation.

Fig 4

A. Cell count according to the presence of glucose or not (galactose) in the culture medium. Results are means ± SEM. In galactose + 10% FCS medium, proliferation of neonatal ASMC (open circles, n = 6) is still present, unlike in adult ASMC (closed circles, n = 4). *p < 0.05 neonate vs. adult at the corresponding time using MANOVA. B. DNA synthesis according to the presence or absence of glucose in the culture medium. Values are means ± SEM. After 24h in a glucose-free (galactose) medium, neonatal ASMC (white bars, n = 5), DNA synthesis is still present, in contrast with adult ASMC (black bars, n = 3). *p < 0.05 using Mann-Whitney U-test.