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. 2015 Mar 23;10(3):e0120239. doi: 10.1371/journal.pone.0120239

Fig 5. Zinc-mediated inhibition of human α1β2 and α1β2γ2S GABAAR signalling in Xenopus oocytes.

Fig 5

(A) Representative trace of the inhibition mediated 100 μM Zn2+ of the currents elicited by 10 μM GABA (EC80) through the α1β2 GABAAR. (B) Representative trace of the inhibition mediated 100 μM Zn2+ of the currents induced by 100 μM GABA (EC80) through the α1β2γ2S GABAAR. (C) The degree of inhibition mediated by 100 μM Zn2+ of GABA EC80-evoked currents in oocytes expressing α1β2 mean ± S.E.M.; 77 ± 6.3%; N = 7and α1β2γ2S (mean ± S.E.M.; 4.7 ± 4.6%; N = 6) GABAARs.