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. 2015 Mar 23;10(3):e0120548. doi: 10.1371/journal.pone.0120548

Fig 3. Telomere types of the linear replicons.

Fig 3

Alignment of the telomeres of the linear replicons in B. afzelii K78 is shown. The sequences are oriented such that their hairpin bend would be positioned to their left side. The typing corresponds to the classification of the telomere types 1–3 according to the spacing between Box 1 (yellow) and Box 3 (blue) or the absence of Box 1 [68, 99, 101]. For five of the sequences the utmost left residue could not be determined and is represented by a “-”as placeholder. Box 1 and Box 3 correspond to previously annotated regions of conservation which are assumed to be directly (Box 3) or indirectly (Box 1) involved in interaction with the telomere resolvase ResT [100, 102]. No telomere data could be obtained for K78 lp28 and the telomeres of lp54L and lp38R are identical. In Box 1 two different sequences, TAT(A/T)AT, are present as in B31. Unlike in B31, where the TATTAT sequence is exclusively found in type 2 telomeres, this sequence is also found in type 1 telomeres of K78. lp28–1L of K78 is an exception while it is compatible with both the definition of type 1 and type 2 telomeres as also seen on lp28–3R of B31 and lp28–2R of PKo. Within the 16 telomeres, 6 have substitutions in Box 3 (5 with one change, and 1 with two changes, marked green).