Table 5. Relation with Arsenic serum levels.
| 1- Association with rs5351 (NM_001201397.1:c.1101A>G) of EDNRB gene. | |||||
|---|---|---|---|---|---|
| Genotype | N | BMI | % non obese | % obese | Obesity OR (95% CI) |
| A) Individuals with high arsenic levels | |||||
| GG | 157 | 27.15 (0.36) | 115 (30.4%) | 42 (43.8%) | 1.00 |
| AG-AA | 319 | 26.59 (0.22) | 265 (69.6%) | 54 (56.2%) | 0.51 (0.32–0.82) |
| 0.08 | 0.0054 | ||||
| B) Individuals with medium arsenic levels | |||||
| GG | 170 | 26.77 (0.35) | 133 (34.2%) | 37 (43.0%) | 1.00 |
| AG-AA | 305 | 26.32 (0.23) | 256 (65.8%) | 49 (57.0%) | 0.70 (0.43–1.13) |
| 0.29 | 0.15 | ||||
| C) Individuals with low arsenic levels | |||||
| GG | 152 | 25.98 (0.37) | 123 (31.1%) | 29 (38.7%) | 1.00 |
| AG-AA | 318 | 25.92 (0.23) | 272 (68.9%) | 46 (61.3%) | 0.70 (0.41–1.20) |
| 0.71 | 0.20 | ||||
Association between obesity and BMI and SNPs of EDNRB genes adjusted by age and sex. OR, odds ratio. Values are mean ± standard error. Bold indicates significance.