Skip to main content
. 2015 Mar 23;10(3):e0119703. doi: 10.1371/journal.pone.0119703

Table 4. Association of the SNPs with CCT, VCDR, IOP, AL in controls and POAG (HTG/NTG/combined).

SNP Minor allele Control (n = 371) NTG (n = 31) HTG (n = 66) Combined (n = 97)
β SE P * β SE P * β SE P * β SE P *
CCT N = 369 N = 27 N = 63 N = 87
rs1900004 T 0.34∞ 0.46∞ 0.31¶ 0.29£
rs3858145 G 0.16¶ 0.48£ 0.21£ 0.32∞
rs10483727 C 0.21∞ 0.59£ 0.08£ 0.15¶
rs1063192 C 0.17∞ 0.11£ 0.08∞ 0.27∞
rs9607469 A 0.4£ 0.79¶ 0.53£ 0.27£
rs1192415 G 0.11 ∞ 0.65£ 0.38∞ 0.14∞
VCDR N = 363 N = 21 N = 45 N = 66
rs1900004 T −0.028 0.012 0.013¶ .39∞ 0.41¶ 0.48¶
rs3858145 G 0.18∞ .42£ 0.39£ 0.43¶
rs10483727 C 0.27£ −0.102 0.04 0.017∞ 0.3∞ −0.062 0.025 0.014∞
rs1063192 C 0.19¶ 0.13£ 0.18£ 0.52£
rs9607469 A 0.27£ 0.4£ −0.141 0.06 0.022∞ 0.07∞
rs1192415 G 0.12∞ 0.16¶ 0.52£ 0.34¶
IOP N = 369 N = 27 N = 54 N = 81
rs1900004 T 0.2£ 0.23¶ −0.042 0.02 0.042¶ 0.29£
rs3858145 G 0.62∞ 0.21¶ 0.2£ 0.27∞
rs10483727 C 0.11£ 0.23∞ 0.07∞ 0.75∞
rs1063192 C 0.14£ 0.72£ 0.59∞ 0.36£
rs9607469 A 0.69£ 0.57£ 0.21£ 0.68∞
rs1192415 G 0.21¶ 0.15∞ 0.51£ 0.59£
AL N = 74 N = 39
rs1900004 T 0.49∞ - - 0.11∞
rs3858145 G 0.29£ - - 0.45£
rs10483727 C 0.26∞ - - 0.21∞
rs1063192 C −0.388 0.15 0.012¶ - - 0.17£
rs9607469 A 0.22£ - - 0.46∞
rs1192415 G 0.62£ - - 0. 07£

β = standard regression coefficient

SE = standard error

£- dominant model

∞- recessive model

¶-additive model

*Obtained from linear regression

Bonferroni adjusted significant level< = 0.008 (0.05/6)