Table 2. Univariate Cox proportional analysis for 30-day mortality and neurologic outcomes.
| Variables | 30-day Mortality | 30-day CPC score | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | p-value | HR | 95% CI | p-value | |
| Age | 1.028 | 1.005–1.054 | 0.016* | 1.028 | 1.012–1.045 | <0.001 * |
| Sex (Female) | 1.235 | 0.589–2.587 | 0.577 | 0.895 | 0.518–1.547 | 0.691 |
| Hypertension | 1.069 | 0.539–20123 | 0.8479 | 1.303 | 0.815–2.082 | 0.2691 |
| Diabetic mellitus | 1.42 | 0.697–2.889 | 0.3339 | 1.286 | 0.773–2.140 | 0.3326 |
| Pulmonary disease | 0.443 | 0.025–7.791 | 0.5782 | 0.782 | 0.191–3.204 | 0.7323 |
| Malignancy | 1.507 | 0.359–6.324 | 0.575 | 1.622 | 0.588–4.479 | 0.3504 |
| Cardiovascular disease | 0.837 | 0.364–1.924 | 0.6751 | 1.041 | 0.603–1.798 | 0.8842 |
| Previous ACS | 0.635 | 0.151–2.661 | 0.534 | 1.033 | 0.444–2.404 | 0.9403 |
| Renal disease | 0.573 | 0.201–1.630 | 0.2964 | 0.868 | 0.473–1.592 | 0.6478 |
| Cardiac origin | 0.748 | 0.381–1.469 | 0.3996 | 0.8/76 | 0.548–1.399 | 0.5788 |
| Cardiac arrest in public place | 0.969 | 0.48–1.955 | 0.93 | 1.254 | 0.781–2.015 | 0.349 |
| Prehospital ROSC | 2.068 | 0.114–37.356 | 0.623 | 2.068 | 0.114–37.356 | 0.623 |
| CPR rhythm (Shockable) | 0.414 | 0.16–1.07 | 0.069 | 0.574 | 0.32–1.031 | 0.063 |
| Total CPR time in hospital | 1.009 | 0.981–1.038 | 0.533 | 1.003 | 0.982–1.024 | 0.793 |
| Arrest time | 1.014 | 0.993–1.036 | 0.188 | 1.003 | 0.989–1.018 | 0.646 |
| Bystander CPR | 1.719 | 0.793–3.727 | 0.17 | 1.461 | 0.831–2.567 | 0.188 |
| Hypothermia | 0.741 | 0.378–1.455 | 0.384 | 0.809 | 0.506–1.292 | 0.374 |
| Witness | 1.338 | 0.674–2.656 | 0.405 | 1.224 | 0.756–1.982 | 0.41 |
| BUN, mg/dL | 0.992 | 0.974–1.01 | 0.375 | 0.997 | 0.986–1.007 | 0.536 |
| Cr, mg/dL | 0.924 | 0.815–1.048 | 0.219 | 0.978 | 0.914–1.046 | 0.512 |
| Albumin, g/dL | 0.69 | 0.432–1.102 | 0.12 | 0.803 | 0.569–1.131 | 0.209 |
| Platelet count | 0.989 | 0.978–1 | 0.057 | 0.995 | 0.985–1.005 | 0.30 |
| Haematocrit, % | 0.997 | 0.964–1.031 | 0.853 | 0.995 | 0.973–1.018 | 0.673 |
| RDW day 1, % | 1.125 | 0.928–1.363 | 0.232 | 1.075 | 0.938–1.232 | 0.30 |
| WBC day 1 | 0.951 | 0.895–1.010 | 0.102 | 1.020 | 0.952–1.056 | 0.263 |
| DNI day 1, % | 1.049 | 1.02–1.08 | 0.001* | 1.041 | 1.016–1.066 | 0.001* |
| DNI day 2, % | 1.036 | 1.015–1.057 | <0.001* | 1.021 | 1.003–1.039 | 0.023* |
| DNI day 3, % | 1.082 | 1.042–1.124 | <0.001* | 1.026 | 0.998–1.055 | 0.072 |
| DNI day peak, (%) | 1.031 | 1.01–1.052 | 0.004* | 1.012 | 0.996–1.029 | 0.142 |
| DNI peak, day (day) | 1.046 | 0.977–1.12 | 0.196 | 1.01 | 0.942–1.082 | 0.787 |
| Antibiotics prophylaxis | 0.568 | 0.174–1.852 | 0.3485 | 0.966 | 0.482–1.938 | 0.9235 |
| Inotrophics | 0.859 | 0.264–2.792 | 0.8 | 1.055 | 0.559–1.991 | 0.8686 |
| APACHE II | 1.01 | 0.957–1.066 | 0.7183 | 0.998 | 0.962–1.036 | 0.9277 |
CPC: cerebral performance category, ACS: acute coronary syndrome, ROSC: return of spontaneous circulation, CPR: cardiopulmonary resuscitation, BUN: blood urea nitrogen, Cr: creatinine, RDW: red cell distribution width, APACHE II: Acute Physiology and Chronic Health Evaluation II, DNI: delta neutrophil index
*: p<0.05.