Table 2.
Lipoprotein and Cholesterol Efflux Capacity and Oxidative Stress Measures
| Mean ± STD or % | ||
|---|---|---|
| On lipid lowering meds? | ||
| Yes (30%) | No (70%) | |
| VLDL & Chylomicron Particles (total)nmol/L | 90.2+/−59.3 | 70.3+/−42.4 |
| Large VLDL & Chylomicrons Particles nmol/L | 6.7+/−7.6 | 5.1+/−6.9 |
| Medium VLDL Particles nmol/L | 43.2+/−39.8 | 30.2+/−23.5 |
| Small VLDL Particles nmol/L | 40.2+/−23.7 | 35+/−24.8 |
| LDL Particles (total) nmol/L | 1139.6+/−301.3 | 1255.5+/−393.4 |
| IDL Particles nmol/L | 97.5+/−77.5 | 120.4+/−83.5 |
| Large LDL Particles nmol/L | 365.6+/−268.2 | 396+/−246.1 |
| Small LDL Particles nmol/L | 676.3+/−362.7 | 739.2+/−404.9 |
| HDL Particles (total) umol/L | 34.1+/−7.7 | 32.5+/−6.8 |
| Large HDL Particles umol/L | 4.8+/−3.7 | 4+/−2.8 |
| Medium HDL Particles umol/L | 11.5+/−5.4 | 11.9+/−6.5 |
| Small HDL Particles umol/L | 17.8+/−6.6 | 16.6+/−5.5 |
| VLDL Size nm | 50+/−7 | 48.6+/−8.1 |
| LDL Size nm | 20.4+/−0.6 | 20.5+/−0.6 |
| HDL Size nm | 9+/−0.5 | 8.9+/−0.5 |
| Triglyceride (total) mg/dL | 170.4+/−95.7 | 140.1+/−75.5 |
| VLDL & Chylomicron Triglyceride (total) mg/dL | 137.6+/−98.4 | 105.3+/−75.6 |
| HDL Cholesterol (total) mg/dL | 48.6+/−15.2 | 44.7+/−12.5 |
| Cholesterol Efflux Capacity | 1+/−0.2 | 1+/−0.2 |
| 8-oxo-deoxyguanine [break frequency (BF)] | 0.12+/−0.23 | 0.08+/−0.12 |
| 8-oxo-dG(BF) <=0 | 37% | 45% |
| >0 | 63% | 55% |
| 8-oxo-dG(BF) <=0.1 | 70% | 75% |
| >0.1 | 30% | 25% |
| OXPHOS Complex I activity (optical density (O.D.)/mg protein x 10^3) | 67.81+/−27.4 | 68.99+/−27.05 |
| OXPHOS Complex IV activity (O.D./mg protein x 10^3) | 49.66+/−17.53 | 49.85+/−17.78 |