Table 3.
Mitochondrial Oxidative Stress and Function and Clinical Lipid Panel in Men and Women with HIV infection on stable HAART (adjusted for age, gender, nadir CD4, CD4, viral load, high blood pressure, diabetes, HOMA, smoking, and lipid lowering medications)
| 8-Oxo-dG (BF) OR, (p value) |
Complex I Activity (O.D.)/μg protein x 103) β, (p value) |
Complex IV Activity (O.D.)/μg protein x 103) β, (p value) |
|
|---|---|---|---|
| Total Cholesterol (mg/dL) | OR=0.99 (p=0.16) | β =−0.1 (p=0.09) | β =−0.05 (p=0.21) |
| LDL Cholesterol (mg/dL) | OR=0.99 (p=0.31) | β =−0.12 (p=0.07) | β =−0.07 (p=0.11) |
| HDL Cholesterol (mg/dL) | OR=0.96 (p<0.01) | β =−0.07 (p=0.65) | β =−0.08 (p=0.41) |
| Triglycerides (mg/dL) | OR=1.00 (p=0.28) | β =−0.01 (p=0.64) | β =0.00 (p=0.95) |
| Total/HDL Cholesterol Ratio | OR=1.42 (p=0.02) | β <0.01 (p=1.0) | β =0.4 (p=0.67) |