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. 2015 Mar 18;10:2173–2190. doi: 10.2147/IJN.S77152

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© 2015 Ma et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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In vitro cytotoxicity of free PTX, PAMAM-PTX, PEG-PAMAM-PTX, and TMAB-PEG-PAMAM-PTX conjugates toward HER2-positive BT474 breast cancer cells.

Notes: The data are presented as the means ± SD. *P<0.05 compared to free paclitaxel.

Abbreviations: PTX, paclitaxel; PAMAM, polyamidoamine; PEG, polyethylene glycol; TMAB, trastuzumab; HER2, human epidermal growth factor 2; SD, standard deviation; IC₅₀, half-maximal inhibitory concentration.