Table II.
Examples of Licensed Oral Dosage Forms for Pediatric Use
| Dosage form | Age | Active ingredient | Comment | Supplier |
|---|---|---|---|---|
| Solids | ||||
| Capsules | ≥6 years | Methylphenidate | SODAS® (Spheroidal Oral Drug Absorption System) technology, 50% IR beads, 50% enteric coated, DR | Ritalin LA® (Novartis) |
| Chewable tablet | >6 months | Montelukast | Singulair® 4-mg chewable tablets (Merck Sharp and Dohme) | |
| >2 years | Cetirizine | Zyrtec® chewable tablets (Pfizer) | ||
| <6 years | Carbamazepine | Tegretol® (Novartis) | ||
| Chewing gum | ≥6 years | Dimenhydrinate | Superpep® travel gum (Hermes) | |
| ≥2 years | Simethicone | Pedia Lax® (Fleet) | ||
| Microcapsules/-spheres | >1 year | Ciprofloxacin | Constitution to a suspension | Cipro® Bayer |
| >3 months | Cefuroxime | Stearic acid-coated microspheres: taste-masking and drug release in lower GIT | Ceftin® (GlaxoSmithKline) | |
| ODF | ≥0.5 years | Ondansetron | Setofilm® (APR and Labtec and Monosol Rx) | |
| ≥2 years | Sennosides | Pedia Lax® (Fleet) | ||
| ≥4 years | Diphenhydramine/Phenylephrine | Triaminic® Thin Strips™ cold and cough (Novartis) | ||
| ODT/melting tablet | ≥6 years (2 years; 0.5 months*) | Prednisolone | Orapred® ODT (Concordia Inc.) | |
| >2 years | Ondansetron | Ondansetron ratiopharm® ODT | ||
| ≥6 years | Ibuprofen | Nurofen® (Reckitt Benckiser) | ||
| >6 years | Desloratadine | Clarinex® (GlaxoSmithKline) | ||
| >1 year | Lansoprazole | Delayed-release ODT (e.g., suspended in oral syringe) | Prevacid® (Takeda) | |
| Sprinkle capsules | ≥2 years | Topiramat | Topamax® (Janssen-Cilag) | |
| >1 year | Lansoprazole | Delayed-release granules | Prevacid® (Takeda) | |
| Tablet | ≥6 years | Ibuprofen | IBU-ratiopharm® (Ratiopharm) | |
| ≥6 years | Sertraline | Scored tablet | Zoloft® (Pfizer) | |
| Liquids | ||||
| Suspension/solutions | > birth** | Antibiotics, e.g., amoxicillin | Constitution to a suspension | Multiple suppliers |
| Glucose/electrolytes | Mixture to be dissolved in water | Oralpädon® (Stada) | ||
IR instant release, DR delayed release, GIT gastrointestinal tract, ODT orodispersible tablets
*Cautious use only
**“From full-term birth and for pre-term neonates who are able to swallow and accept enteral feeding” (16)