Table 2.
Incidence of Primary and Secondary Outcomes Across Diet Drink Consumption Strata
| Outcomes | Diet drink consumption | ||||
|---|---|---|---|---|---|
| 0–3/month | 1–4/week | 5–7/week | ≥2/day | p value* | |
| Total subjects | 38,337 | 11,590 | 6,702 | 2,985 | |
| Cardiovascular events (%) | |||||
| Combined | 2,745 (7.2) | 785 (6.8) | 462 (6.9) | 254 (8.5) | 0.010 |
| CHD | 1,030 (2.7) | 279 (2.4) | 159 (2.4) | 94 (3.1) | 0.055 |
| HF | 349 (0.9) | 95 (0.8) | 53 (0.8) | 37 (1.2) | 0.13 |
| MI | 819 (2.1) | 219 (1.9) | 122 (1.8) | 74 (2.5) | 0.065 |
| Coronary revascularization | 1,039 (2.7) | 325 (2.8) | 204 (3.0) | 111 (3.7) | 0.008 |
| Stroke | 652 (1.7) | 192 (1.7) | 94 (1.4) | 58 (1.9) | 0.212 |
| PAD | 160 (0.4) | 49 (0.4) | 27 (0.4) | 22 (0.7) | 0.079 |
| Cardiac death | 642 (1.7) | 163 (1.4) | 90 (1.3) | 47 (1.6) | 0.076 |
| Mortality (%) | |||||
| All cause death | 2,970 (7.7) | 789 (6.8) | 445 (6.6) | 233 (7.8) | 0.003 |
CHD coronary heart disease, HF heart failure, MI myocardial infarction, PAD peripheral arterial disease
*Unadjusted p values (χ2 test)