Fig. 2. Glioblastoma multiforme cells unlike neural stem cells generated tumor mass in orthotopic brain xenograft models. Hematoxylin and eosin (H&E) and immunohistochemistry staining for proliferating cell nuclear antigen (PCNA) expression were performed in representative whole brains of the orthotopic xenograft. Bar chart summary of average staining intensity of PCNA in 3 randomly selected hot spot regions (*P<0.05).
