The adjusted mean values of reaction time (in ms) obtained from the implicit association test according to the dose of BZDs used in 2823 NESDA participants. The size of each square is proportional to the number of participants. Vertical lines indicate standard errors. Analyses were adjusted for sociodemographic variables (i.e. gender, age, education), health indicators (i.e. daily alcohol use, presence of somatic disease), psychopathology (i.e. IDS-mc, BAI), antidepressant use (in four categories) and duration of BZD use. Low dose was defined as ≤5 mg diazepam equivalents day−1, intermediate dose as 5.01–10 mg day−1 and high dose as >10 mg day−1. β coefficients and P values by multivariate linear regression analysis