Table 3A.
Evolution of vinflunine dose schedule during the study in patients in group 1
| Evolution of vinflunine dose schedule during study Group 1 starting dose at cycle 1 = 280 mg m−2 | n | % |
|---|---|---|
| Decrease to 210 mg m−2 at cycle 2 – up to cycle 3 | 1 | 7.7 |
| Decrease to 250 mg m−2 at cycle 2 – up to cycle 2 | 2 | 15.4 |
| Decrease to 250 mg m−2 at cycle 2 – up to cycle 4 | 1 | 7.7 |
| Increase to 320 mg m−2 at cycle 2 – up to cycle 2 | 3 | 23.1 |
| Increase to 320 mg m−2 at cycle 2 – up to cycle 3 | 1 | 7.7 |
| Increase to 320 mg m−2 at cycle 2 – up to cycle 6 | 1 | 7.7 |
| Increase to 320 mg m−2 at cycle 2, decrease to 280 mg m−2 at cycle 3 – up to cycle 4 | 1 | 7.7 |
| Increase to 320 mg m−2 at cycle 2, decrease to 280 mg m−2 at cycle 3 – up to cycle 7 | 1 | 7.7 |
| Not treated after cycle 1 | 2 | 15.4 |
| Number of patients | 13 | 100.0 |