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Haematological toxicities (worst grade on study by patient)
| Haematological parameter | Group 1 Moderate renal impairment n = 13 | Group 2 Severe renal impairment n = 20 | ||||
|---|---|---|---|---|---|---|
| Grade ≥ 1 n (%) | Grade 3 n (%) | Grade 4 n (%) | Grade ≥ 1 n (%) | Grade 3 n (%) | Grade 4 n (%) | |
| Anaemia | 12 (100) | 4 (30.8) | – | 20 (100) | 2 (10) | – |
| Leucopenia | 10 (76.9) | 2 (15.4) | 3 (23.1) | 18 (90) | 10 (50) | 3 (15) |
| Neutropenia | 12 (92.3) | 6 (46.2) | 3 (23.1) | 17 (85) | 5 (25) | 10 (50) |
| Thrombocytopenia | 9 (69.2) | 2 (15.4) | – | 13 (65) | – | – |
