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. 2015 Mar 24;9:12. doi: 10.3389/fncir.2015.00012

Figure 2.

Figure 2

Glycinergic inhibition mediates auditory processing in the M-cell. (A) Sample intracellular recordings from the Mauthner-cell (M-cell) soma in response to an individual sound pip before (black trace) and after (red trace) treatment with strychnine. The insetshows the initial part of the evoked response at an expanded time scale. Light and dark shaded areas distinguish the initial (EPSP; 0–5 ms) and later components (mixed PSP; >5 ms) of the response, respectively. Bottom traces show sound stimulus (200 Hz single-cycle “pip” at 80 dB re: 20 μPa). (B) Plots of mean (± SEM, N = 9) overall peak amplitude of sound-evoked depolarization in control (black bar) and strychnine (red bar) conditions. (C) Plots of mean (± SEM, N = 9) PSP duration (Tau) before (black) and after (red) treatment with strychnine. (D) Plots of the mean (± SEM, N = 9) relative change in sound-evoked depolarization for the initial (EPSP) and later parts (mixed PSP) of the sound response after treatment with strychnine. Asterisks indicate p values in statistical comparisons that were < 0.01 (**), < 0.001 (***).