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Kaplan-Meier survival curves. The effect of RARβ2 hypermethylation on RFS was analyzed using a log-rank test in (A) 151 never-smokers, (B) 427 ever-smokers, (C) 128 never-smokers with adenocarcinoma, and (D) 23 never-smokers with other cell types. The minus and plus signs indicate the absence and presence of RARβ2 hypermethylation, respectively. P values were based on the log-rank test.
