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. Author manuscript; available in PMC: 2015 Jun 15.
Published in final edited form as: Biochem J. 2014 Jun 15;460(3):447–457. doi: 10.1042/BJ20140360

Figure 9.

Figure 9

The modeled concentrations (in silico data) of (−)-cocaine, cocaethylene, and norcocaine in human blood when the initial concentrations of (−)-cocaine, cocaethylene, and norcocaine are 61, 34, and 5 μM, respectively. (A) to (C) refer to the time-dependent concentrations in the presence of wild-type human BChE (without E12-7), whereas (D) to (F) refer to the time-dependent concentrations in the presence of 0.07 μM E12-7.