Table 2.
Extent of conjugation of xanthohumol and its metabolites in plasma samples at different time points (1 and 24 hr) following a single oral administration of 60 (n=2) or 180 (n=2) mg XN
Metabolite | % Conjugation | |||
---|---|---|---|---|
60 mg XN | 180 mg XN | |||
| ||||
1hr plasma | 24 hr plasma | 1hr plasma | 24 hr plasma | |
Xanthohumol (XN) | 100 | 100 | 96 ± 3 | 100 |
Isoxanthohumol (IX) | 100 | 100 | 100 | 100 |
8-prenylnaringenin (8PN) | 100 | 100 | 100 | 100 |
Values are reported as mean of biological replicates ± SEM. Samples were analyzed in triplicate.