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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Cytokine Growth Factor Rev. 2014 Aug 15;25(5):587–596. doi: 10.1016/j.cytogfr.2014.08.002

Table 1.

A summary of the manner of cell death induced by EV infection in the indicated cell types.

Cell type Cell death Reference
Murine cardiomyocyte line (HL-1) Apoptosis 18, 82
In vivo murine cardiomyocytes Apoptosis 19, 20, 99
Biopsied human cardiomyocytes Apoptosis 21
Primary rat β-cells Intrinsic apoptosis 31
Biopsied human pancreatic islets Likely apoptosis, by nuclear morphology 33, 34
In vivo murine neurons and neuronal stem cells Apoptosis 41, 49, 52
Human neuronal cell lines (IMR5, SK-N-MC) Apoptosis 42, 47
Human glioblastoma cell line (SF268) Apoptosis 48
Human cervical adenocarcinoma cell line (HeLa) Apoptosis 6168, 75, 80, 86, 102, 121, 124
Human cervical adenocarcinoma cell line (HeLa) Caspase-independent apoptosis 68
In vivo murine pancreatic tissue Apoptosis 98, 99
Human intestinal epithelial cell line (Caco-2) Necrosis 102
Human kidney cell line (HEK293) Apoptosis 126