Table 2.
Ribosome residence time at position 6 (A) and 5 (B)
| A | ||||
|---|---|---|---|---|
| Codon | AA | Usage | RRT | p value |
| CTC | Leu | 5.4 | 1.89 | *0.0001 |
| CCC | Pro | 6.8 | 1.71 | *0.0001 |
| GGG | Gly | 6 | 1.61 | *0.0001 |
| AGG | Arg | 9.2 | 1.59 | *0.0001 |
| ATA | Ile | 17.8 | 1.57 | *0.0001 |
| GGA | Gly | 10.9 | 1.56 | *0.0001 |
| TGG | Trp | 10.4 | 1.53 | *0.0001 |
| GTG | Val | 10.8 | 1.52 | *0.0001 |
| CGC | Arg | 2.6 | 1.45 | *0.0001 |
| CGA | Arg | 3 | 1.45 | *0.0008 |
| CGG | Arg | 1.7 | 1.44 | *0.0010 |
| TCG | Ser | 8.6 | 1.43 | *0.0001 |
| CCA | Pro | 18.3 | 1.38 | *0.0001 |
| ACA | Thr | 17.8 | 1.35 | *0.0001 |
| CCG | Pro | 5.3 | 1.31 | *0.0001 |
| GTA | Val | 11.8 | 1.31 | *0.0001 |
| GCA | Ala | 16.2 | 1.28 | *0.0001 |
| CCT | Pro | 13.5 | 1.27 | *0.0001 |
| TCA | Ser | 18.7 | 1.26 | *0.0001 |
| TAC | Tyr | 14.8 | 1.25 | *0.0001 |
| TAT | Tyr | 18.8 | 1.25 | *0.0001 |
| GAG | Glu | 19.2 | 1.25 | *0.0001 |
| CTA | Leu | 13.4 | 1.25 | *0.0001 |
| CTT | Leu | 12.3 | 1.24 | *0.0001 |
| TGC | Cys | 4.8 | 1.23 | *0.0001 |
| GGC | Gly | 9.8 | 1.22 | *0.0001 |
| CAG | Gln | 12.1 | 1.15 | *0.0002 |
| ACG | Thr | 8 | 1.12 | 0.0069 |
| AGT | Ser | 14.2 | 1.10 | 0.0060 |
| AGC | Ser | 9.8 | 1.09 | 0.0213 |
| CAC | His | 7.8 | 1.08 | 0.0098 |
| TTT | Phe | 26.1 | 1.05 | 0.0529 |
| GAA | Glu | 45.6 | 1.04 | 0.0538 |
| AGA | Arg | 21.3 | 1.01 | 0.3014 |
| TTC | Phe | 18.4 | 1.00 | 0.4955 |
| GCG | Ala | 6.2 | 0.99 | 0.4650 |
| TCC | Ser | 14.2 | 0.99 | 0.3341 |
| TTA | Leu | 26.2 | 0.99 | 0.3166 |
| TCC | Ser | 23.5 | 0.98 | 0.2249 |
| CAT | His | 13.6 | 0.93 | 0.0188 |
| GGT | Gly | 23.9 | 0.93 | *0.0003 |
| ATG | Met | 20.9 | 0.92 | 0.0027 |
| ATT | Ile | 30.1 | 0.92 | *0.0005 |
| TTG | Leu | 27.2 | 0.92 | *0.0001 |
| CTG | Leu | 10.5 | 0.92 | 0.0139 |
| AAT | Asn | 35.7 | 0.88 | *0.0001 |
| AAA | Lys | 41.9 | 0.88 | *0.0003 |
| CGT | Arg | 6.4 | 0.87 | *0.0002 |
| CAA | Gln | 27.3 | 0.87 | *0.0001 |
| GCC | Ala | 12.6 | 0.86 | *0.0001 |
| GAC | Asp | 20.2 | 0.85 | *0.0001 |
| TGT | Cys | 8.1 | 0.81 | *0.0001 |
| GCT | Ala | 21.2 | 0.81 | *0.0001 |
| ATC | Ile | 17.2 | 0.80 | *0.0001 |
| ACT | Thr | 20.3 | 0.78 | *0.0001 |
| GAT | Asp | 37.6 | 0.76 | *0.0001 |
| AAC | Asn | 24.8 | 0.76 | *0.0001 |
| GTT | Val | 22.1 | 0.75 | *0.0001 |
| GTC | Val | 11.8 | 0.75 | *0.0001 |
| AAG | Lys | 30.8 | 0.74 | *0.0001 |
| ACC | Thr | 12.7 | 0.70 | *0.0001 |
| B | ||||
|---|---|---|---|---|
| Codon | AA | Usage | RRT | p value |
| CCT | Pro | 13.5 | 1.80 | *0.0001 |
| CCC | Pro | 6.8 | 1.48 | *0.0001 |
| CCA | Pro | 18.3 | 1.48 | *0.0001 |
| AAT | Asn | 35.7 | 1.39 | *0.0001 |
| CGC | Arg | 1.7 | 1.34 | 0.0070 |
| CCG | Pro | 5.3 | 1.30 | *0.0001 |
A. Usage of each codon per 1000 codons and the Ribosome Residence Time (RRT) at position 6 (the A-site of the ribosome). The p-value for a difference between the calculated RRT value and an RRT value of 1 is shown. p-values less than or equal to 0.001 are marked with an asterisk. B. As for A, but for the six highest values at position 5 (the P-site).