Fig. 3.

OXTR methylation predicts amygdala connectivity within brain regions important for emotion regulation and face perception. Z statistic map of voxels shows a significant negative main effect of OXTR methylation on right amygdala functional connectivity for faces > ovals contrast within ROI, FDR corrected at q < 0.05. Images are depicted in MNI space (Top, x = –3, y = 14, z = –7; Middle, x = –20, y = 22, z = 2; Bottom, x = –36, y = –74, z = –16). (Inset) Right amygdala seed region (y = –4). ACC, anterior cingulate cortex; C/Pu, caudate/putamen; FG, fusiform gyrus; IFG, inferior frontal gyrus; Ins, insular cortex; LOC, lateral occipital cortex; OFC, orbitofrontal cortex; pAC, paracingulate gyrus; Thal, thalamus.