For all 4 studied biomarkers, biomarker concentrations are compared between 4 groups: patients with no AKI by SCr or CysC rise; patients who only have acute kidney injury by SCr rise; patients who only have acute kidney injury by CysC rise; patients who have acute kidney injury using both methods. The p-values within the graphs are from performance of a non-parametric test for trend across groups.
NGAL: neutrophil gelatinase-associated lipocalin; AKI: acute kidney injury; SCR-AKI: acute kidney injury defined by rise in serum creatinine from baseline; CysC-AKI: acute kidney injury defined by rise in serum cystatin C from baseline; SCr+CysC-AKI: acute kidney injury defined by rise in serum creatinine and Cystatin C from baseline; IL-18: interleukin-18; KIM-1: kidney injury molecule-1; CysC: cystatin C.