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Glutathione S-transferase (GST)-catalyzed macrocyclization. The macrocyclic peptide is generated by GST-catalyzed SNAr reaction between the cysteine thiol of an N-terminal glutathione (γ-Glu-Cys-Gly) tag and a perfluoroaryl moiety linked to the C-terminal cysteine. Circles represent amino acids.
