. Author manuscript; available in PMC: 2015 Mar 24.

Published in final edited form as: Mol Imaging Biol. 2014 Dec;16(6):813–820. doi: 10.1007/s11307-014-0743-2

Table 2.

K₁/k₂, k₃/k₄, and V_T obtained from ¹⁸F-VUIIS1008 (n = 5) and ¹⁸F-VUIIS1008 in pre-blocking study (n = 2). Results = Mean ± SEM.

Probe	Region	K₁/k₂	k₃/k₄	V_T=(K₁/k₂)(1+k₃/k₄)	%ID/cc (90 min)
¹⁸F-VUIIS1008^a	Brain	0.855 ± 0.325	4.435 ± 1.387	4.210 ± 1.612	0.103 ± 0.031
¹⁸F-VUIIS1008^a	Tumor	1.902 ± 0.816	12.634 ± 1.406	25.224 ± 10.035	0.310 ± 0.051
¹⁸F-DPA-714^b	Brain	3.619 ± 0.551	4.024 ± 0.842	15.963 ± 3.566	0.088 ± 0.011
¹⁸F-DPA-714^b	Tumor	6.867 ± 1.226	8.913 ± 1.155	70.033 ± 14.729	0.331 ± 0.036
¹⁸F-VUIIS1008^c (Pre-blocking study)	Brain^d	0.059 – 0.061	4.888 – 13.507	0.380 – 0.615	N/A
¹⁸F-VUIIS1008^c (Pre-blocking study)	Tumor^e	0.124 – 0.143	3.972 – 4.368	0.618 – 0.767	N/A

C6-glioma bearing rats (n = 5). Results = Mean ± SEM

Originally reported in reference [16]. Results = Mean ± SEM

Pre-blocking study with C6-glioma bearing rats (n = 2). Results reflect the range of values from the 2 rats.