Table 5.
Echocardiographic variables of all study participants before (pre), immediately after (post) and 14 days after (follow-up) the marathon
| Parameter | Pre | Post | Follow-up | p (Pre vs. Post) | p (Pre vs. Follow-up) |
|---|---|---|---|---|---|
| LV systolic function | |||||
| FS [%] | 41.5 (37.0-46.5) | 46.0 (40.9-52.0) | 45.0 (37.0-50.0) | <0.001 | 0.001 |
| MPI LV | 0.46 (0.40-0.55) | 0.47 (0.41-0.58) | 0.44 (0.35-0.52) | 0.116 | 0.018 |
| Longitudinal 2D strain septal basal [%] | -17.8 (15.5-20.2) | -19.6 (16.3-22.8) | -18.6 (15.6-21.4) | <0.001 | 0.566 |
| Peak systolic velocity septal basal S’[m/s] | 0.07 (0.07-0.08) | 0.09 (0.08-0.10) | 0.08 (0.07-0.09) | <0.001 | 0.009 |
| LV diastolic function | |||||
| E [m/s] | 0.80 (0.70-0.92) | 0.67 (0.55-0.77) | 0.81 (0.69-0.92) | <0.001 | 0.281 |
| A [m/s] | 0.60 (0.50-0.70) | 0.69 (0.60-0.81) | 0.60 (0.50-0.68) | <0.001 | 0.531 |
| E/A | 1.40 (1.10-1.60) | 0.91 (0.76-1.20) | 1.3 (1.10-1.67) | <0.001 | 0.768 |
| E/E’ | 7.75 (6.63-9.43) | 9.08 (7.41-11.08) | 7.80 (6.87-9.15) | 0.001 | 0.150 |
| E’ septal [m/s] | 0.10 (0.09-0.12) | 0.09 (0.07-0.11) | 0.10 (0.09-0.12) | <0.001 | 0.484 |
| A’ [m/s] | 0.09 (0.07-0.10) | 0.11 (0.09-0.13) | 0.09 (0.08-0.11) | <0.001 | 0.070 |
| DT [ms] | 187.0 (145.3-230.0) | 130.0 (106.8-170.5) | 177.0 (143.0-223.5) | <0.001 | 0.324 |
| Right heart parameters | |||||
| RVEDD [mm] | 32.0 (29.0-38.0) | 31.0 (28.0-35.5) | 34.0 (30.0-38.0) | 0.008 | 0.079 |
| TAPSE [mm] | 28.0 (26.0-31.0) | 28.0 (25.0-29.0) | 28.0 (25.0-30.0) | 0.025 | 0.429 |
| RV S’ [m/s] | 0.11 (0.10-0.12) | 0.11 (0.09-0.13) | 0.11 (0.10-0.13) | 0.958 | 0.325 |
| MPI RV | 0.53 (0.41-0.72) | 0.50 (0.41-0.65) | 0.48 (0.38-0.71) | 0.196 | 0.004 |
| Longitudinal TDI RV strain basal [%] | -24.8 (20.0-29.5) | -23.6 (18.8-29.5) | -26.0 (21.1-30.1) | 0.681 | 0.197 |
| Longitudinal TDI RV strain mid [%] | -32.6 (26.7-39.1) | -29.0 (22.5-34.5) | -32.0 (24.1-37.9) | <0.001 | 0.477 |
| Longitudinal TDI RV strain apical [%] | -32.4 (24.5-32.8) | -26.9 (20.5-32.8) | -27.8 (21.7-35.9) | <0.001 | 0.020 |
Values are shown as median (IQR). Statistically significant values are marked in bold. LV, left ventricular; FS, fractional shortening; MPI, myocardial performance index; E, peak transmitral E-wave velocity; A, peak transmitral A-wave velocity; E/A, ratio of transmitral E to transmitral A; E’ septal, early diastolic annular velocity measured in the septal annulus; A’, late diastolic annular velocity measured in the septal annulus; E/E’, ratio of peak early transmitral diastolic velocity to early septal annular velocity; DT, deceleration time of the transmitral E-wave; RV, right ventricular; RVEDD, RV end diastolic diameter; TAPSE, tricuspid annular plane systolic excursion; RV S’, peak systolic velocity of the basal RV free wall segment.