Table 2. Positional candidate genes related to immunological pathways.
| Pathway | Genes 1 | Function 2 |
|---|---|---|
| Toll-like receptor signaling pathway | TLR1 (6), TLR6 (6), TRAF6 (15) | Chemotactic effects (NK cell, T cell), T cell stimulation, Antiviral effects, Proinflammatory effects |
| Chemokine signaling pathway | ULBP1 (9), PRKACB (3), CCL19/21/27 (8) | Leukocyte transendothelial migration |
| Leukocyte transendothelial migration | RhoH (6), Nox3 (9), EZR (9), CLDN10 (12) | Inflammation, immune surveillance |
| Hematopoietic cell lineage | CD44 (15), GP9 (22) | Differentiation of hematopoietic stem cell into white blood cells, leukocytes-the natural killer (NK) cells, the T and B lymphocytes |
| Cytokine-cytokine receptor interaction | CNTFR (8), KITLG (5) | Intercellular regulators and mobilizers of cells engaged in innate and adaptive inflammatory host defenses |
1Gene ID (Chromosomal location).
2Annotation in KEGG pathway [34].