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. 2015 Mar 24;9(3):e0003611. doi: 10.1371/journal.pntd.0003611

Fig 4. Histopathological analysis of Salmonella induced caecal inflammation of streptomycin-pre-treated mice.

Fig 4

A single representative caecal wall image from each group is shown. A. naïve uninfected mouse. B. Infection with SL1344ΔorgA (SPI-1 mutant derivative). C & D. Infection with SL1344. E. Infection with A130 (lineage 1); F. Infection with D23580 (lineage II). Images A, C, D, E & F were taken at x100 magnification of original size (image B is x50 magnification). Abbreviations: l, intestinal lumen; sm, submucosa; oe, submucosal oedema; pmn (polymorphonuclear leukocytes) infiltrate; sc, surface changes; ca, crypt abcesses. Histopathology score of inflammatory changes in the caecum of streptomycin pretreated C57bl/6 mice (G) or 129P2/olaHsd mice (H) with ST313 isolates or strain SL1344, two or three days post inoculation. The scores of five inflammatory markers according to the key are indicated.