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. 2015 Mar 24;10(3):e0119490. doi: 10.1371/journal.pone.0119490

Fig 1. Flowchart of AMPcore.

Fig 1

2,497 non-redundant experimentally validated AMPs were obtained from CAMP release 2. 798 AMP nested families are recognized through self-comparison and their source proteins from NCBI nr database. The critical regions or cores of the nested families are then determined along with their features such as protein secondary structures and conserved domains. AMPcore are built using CRFs based on the nested AMPs and the performances are examined using 10-fold cross-validation.