Table 1. Feature ablation study of AMPcore on the comprehensive dataset using 10-fold cross-validation.

Features	Sensitivity	Specificity	Accuracy	MCC
All	89.1	90.1	89.6	0.79
− Primary structures	73.5	88.0	80.8	0.62
− Secondary structures	88.4	89.1	88.8	0.78
− Net charges	88.9	88.9	88.9	0.78
− Amphipathicity	88.3	90.0	89.1	0.78
− Conserved domains	88.4	89.5	88.9	0.78
− Aggregation	88.9	89.3	89.1	0.78
− Gapless alignments	89.3	89.6	89.5	0.79
− AMPA	89.0	90.1	89.6	0.79

The symbol ‘−’ stands for “subtracting”.