Table 2. Features ablation study of AMPcore on the low similarity dataset using 10-fold cross-validation.

Features	Sensitivity	Specificity	Accuracy	MCC
All	82.3	84.0	83.2	0.66
− Primary structures	65.3	82.0	73.7	0.48
− Secondary structures	81.2	82.0	81.6	0.63
− Net charges	81.7	82.5	81.1	0.64
− Amphipathicity	81.9	82.2	82.0	0.64
− Conserved domains	81.9	82.5	82.2	0.65
− Aggregation	82.2	83.6	82.9	0.66
− Gapless alignments	82.4	84.0	83.2	0.66
− AMPA	81.3	84.3	82.8	0.66

The symbol ‘−’ stands for “subtracting”.