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. Author manuscript; available in PMC: 2015 Mar 24.
Published in final edited form as: Clin Cancer Res. 2009 Mar 10;15(6):1989–1997. doi: 10.1158/1078-0432.CCR-08-2054

Fig. 1.

Fig. 1

Histopathologic analysis of intracerebral model of lymphomatous growth: infiltration and immunophenotype. A, intracerebral Raji lymphoma growth in brain is diffusely infiltrative into cerebral cortex, midbrain, contralateral hemisphere, and leptomeninges (H&E) and tumors exhibit the characteristic PCNSL immunophenotype. B, CD20+ membrane staining of lymphoma cells with perivascular pattern of infiltration (angiotropism; ×200). C, Bcl-6+ nuclear staining of lymphoma cells that exhibit intense meningeal spread (left; ×100). D, MUM-1+ expression by lymphoma cells (×400).